Syrup manufacturing

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it involves the production of liquid formulations containing sugar or sugar substitutes, often combined with active pharmaceutical ingredients (API), flavorings, preservatives, and other excipients. Syrups are common in the pharmaceutical, nutraceutical, food, and supplement industries.

1. Pharmaceutical Syrups – e.g., cough syrups, vitamin syrups
2. Flavored Syrups – for beverages, desserts, or culinary use
3. Nutraceutical Syrups – supplements like multivitamin tonics
4. Sugar-Free Syrups – for diabetics (contain artificial sweeteners)

1.Preparation of Sugar Base

• Dissolve sugar (or sweetener) in purified water
• Heat if necessary for better solubility
• Filter the solution to remove impurities

• Active ingredients are dissolved or suspended depending on solubility
• Stirring and homogenization are often used

• Flavoring agents
• Colorants
• Preservatives (e.g., sodium benzoate)
• Viscosity agents (e.g., glycerin, sorbitol)
• pH adjusters (e.g., citric acid)

• Filtration through fine mesh or filters to remove particulates
• Deaeration to remove entrapped air (optional, prevents oxidation)

• Sterile or cleanroom conditions for pharmaceutical syrups
• Bottle filling (glass or plastic)
• Capping, labeling, and batch coding

• Sugar melting tanks
• Mixing vessels with agitators
• Inline homogenizers
• Filter press or cartridge filters
• Syrup storage tanks
• Liquid filling machines
• Bottle washing and capping machines
• PLC/SCADA-based control systems
• Clean-in-place (CIP) systems
• Inline sensors for Brix, pH, or viscosity

• Follows GMP (Good Manufacturing Practice)
• Validation of batch records and cleaning
• Microbial testing and quality control for each batch
• Stability studies .