Capsule manufacturing
it refers to the production of solid dosage forms where medicinal or nutritional ingredients are enclosed in a soluble container, typically made of gelatin or a vegetarian substitute like HPMC (hydroxypropyl methylcellulose).
Capsule Manufacturing Process
Soft gel Capsules
- Fill Formulation:
- Active ingredients are mixed with oil or solvent base.
- Encapsulation:
- Rotary die process fills and seals capsules in one step.
- Capsules are dried on trays or tumble dryers.
- Inspection and Packaging:
- Capsules are cleaned, polished, inspected, and packaged.
Key Equipment
- Capsule fillers (fully automatic)
- V-blender mixer
- Tumble dryers
- Inspection machines
- Packaging lines
Quality Control
- Weight variation
- Disintegration time
- Moisture content
- Microbiological testing
- Visual inspection
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